Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic variants. In the current study we have examined the role of a newly discovere...

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Detalles Bibliográficos
Autores principales: Bråten, Line Skute, Ingelman‐Sundberg, Magnus, Jukic, Marin M., Molden, Espen, Kringen, Marianne Kristiansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468554/
https://www.ncbi.nlm.nih.gov/pubmed/35668575
http://dx.doi.org/10.1111/cts.13347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468554/
https://www.ncbi.nlm.nih.gov/pubmed/35668575
http://dx.doi.org/10.1111/cts.13347

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