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Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population
Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic variants. In the current study we have examined the role of a newly discovere...
Autores principales: | Bråten, Line Skute, Ingelman‐Sundberg, Magnus, Jukic, Marin M., Molden, Espen, Kringen, Marianne Kristiansen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468554/ https://www.ncbi.nlm.nih.gov/pubmed/35668575 http://dx.doi.org/10.1111/cts.13347 |
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