Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug–drug interaction studies

N‐Nitrosamine (NA) impurities are considered genotoxic and have gained attention due to the recall of several marketed drug products associated with higher‐than‐permitted limits of these impurities. Rifampicin is an index inducer of multiple cytochrome P450s (CYPs) including CYP2B6, 2C8, 2C9, 2C19,...

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Detalles Bibliográficos
Autores principales: Bolleddula, Jayaprakasam, Gopalakrishnan, Sathej, Hu, Ping, Dong, Jennifer, Venkatakrishnan, Karthik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468573/
https://www.ncbi.nlm.nih.gov/pubmed/35722783
http://dx.doi.org/10.1111/cts.13357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468573/
https://www.ncbi.nlm.nih.gov/pubmed/35722783
http://dx.doi.org/10.1111/cts.13357

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