Green synthesis, structure optimization and biological evalution of Rhopaladins’ analog 2–styryl–5-oxopyrrolidine-2- carboxamide RPDPRH on CaSki cells

We have synthesized Rhopaladins’ analog (2E,4E)-4-chlorobenzylidene-2-(4-chlorostyryl)-N-cyclohexyl-1-(4-fluorophenyl)-5-oxopyrrolidine-2-carboxamide (RPDPRH) via a highly facile, inexpensive and green approach and verified the structural superiority of compound RPDPRH through molecular docking. Mor...

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Detalles Bibliográficos
Autores principales: Ke, Li-Na, Kong, Ling-Qi, Zhu, Xiu-Lian, Wu, Feng-Xu, Chen, Qin-Hua, Li, Bin, Dong, Yun, Wang, Hong-Mei, Zeng, Xiao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468594/
https://www.ncbi.nlm.nih.gov/pubmed/36110131
http://dx.doi.org/10.3389/fchem.2022.975559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468594/
https://www.ncbi.nlm.nih.gov/pubmed/36110131
http://dx.doi.org/10.3389/fchem.2022.975559

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