A novel method to purify small RNAs from human tissues for methylation analysis by LC-MS/MS

Methylation modification of small RNAs, including miRNA, piRNA, and tsRNA, is critical for small RNA biogenesis and biological function. Methylation of individual small RNA can be defined by liquid chromatography-coupled with mass spectrometry (LC-MS/MS). However, LC-MS/MS analysis requires a high p...

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Detalles Bibliográficos
Autores principales: Yang, Rong, Li, Jianfeng, Wu, Yifan, Jiang, Xinli, Qu, Shuang, Wang, Qiang, Liang, Hongwei, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468635/
https://www.ncbi.nlm.nih.gov/pubmed/36111135
http://dx.doi.org/10.3389/fmolb.2022.949181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468635/
https://www.ncbi.nlm.nih.gov/pubmed/36111135
http://dx.doi.org/10.3389/fmolb.2022.949181

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