Akebia saponin D protects hippocampal neurogenesis from microglia-mediated inflammation and ameliorates depressive-like behaviors and cognitive impairment in mice through the PI3K-Akt pathway

Given the ability of akebia saponin D (ASD) to protect various types of stem cells, in the present study, we hypothesized that ASD could promote the proliferation, differentiation, and survival of neural stem/precursor cells (NSPCs), even in a microglia-mediated inflammatory environment, thereby mit...

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Detalles Bibliográficos
Autores principales: Liu, Qin, Zhang, Jinqiang, Xiao, Chenghong, Su, Dapeng, Li, Liangyuan, Yang, Changgui, Zhao, Zhihuang, Jiang, Weike, You, Zili, Zhou, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468712/
https://www.ncbi.nlm.nih.gov/pubmed/36110522
http://dx.doi.org/10.3389/fphar.2022.927419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468712/
https://www.ncbi.nlm.nih.gov/pubmed/36110522
http://dx.doi.org/10.3389/fphar.2022.927419

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