Anti-Osteoclast Effect of Exportin-1 Inhibitor Eltanexor on Osteoporosis Depends on Nuclear Accumulation of IκBα–NF-κB p65 Complex

Osteoporosis affects around 200 million people globally, with menopausal women accounting for the bulk of cases. In the occurrence and development of osteoporosis, a key role is played by osteoclasts. Excessive osteoclast-mediated bone resorption activity reduces bone mass and increases bone fragili...

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Detalles Bibliográficos
Autores principales: Chen, Junchun, Song, Dezhi, Xu, Yang, Wu, Liwei, Tang, Lili, Su, YuanGang, Xie, Xiaoxiao, Zhao, Jinmin, Xu, Jiake, Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468713/
https://www.ncbi.nlm.nih.gov/pubmed/36110547
http://dx.doi.org/10.3389/fphar.2022.896108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468713/
https://www.ncbi.nlm.nih.gov/pubmed/36110547
http://dx.doi.org/10.3389/fphar.2022.896108

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