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The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation

The role of the indirect T-cell recognition pathway of allorecognition in acute T cell-mediated rejection (aTCMR) is not well defined. The amount of theoretical T-cell epitopes available for indirect allorecognition can be quantified for donor-recipient combinations by the Predicted Indirectly ReCog...

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Detalles Bibliográficos
Autores principales: Betjes, Michiel G. H., Peereboom, Emma T. M., Otten, Henny G., Spierings, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468767/
https://www.ncbi.nlm.nih.gov/pubmed/36110856
http://dx.doi.org/10.3389/fimmu.2022.973968