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Citrulline protects against LPS‑induced acute lung injury by inhibiting ROS/NLRP3‑dependent pyroptosis and apoptosis via the Nrf2 signaling pathway

Acute lung injury (ALI) is a common complication in patients with sepsis and is accompanied by high mortality. The present study aimed to investigate if the organic compound citrulline has a protective against lipopolysaccharide (LPS)-stimulated ALI and its potential mechanisms. ALI was induced in m...

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Detalles Bibliográficos
Autores principales: Xue, Yao, Zhang, Yunqian, Chen, Li, Wang, Yan, Lv, Zhou, Yang, Li-Qiao, Li, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468793/
https://www.ncbi.nlm.nih.gov/pubmed/36160882
http://dx.doi.org/10.3892/etm.2022.11569