RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling

Activation of CD40-signaling contributes to the initiation, progression and drug resistance of B cell lymphomas. We contributed to this knowledge by showing that constitutive CD40-signaling in B cells induces B cell hyperplasia and finally B cell lymphoma development in transgenic mice. CD40 activat...

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Detalles Bibliográficos
Autores principales: Kuhn, Laura B., Valentin, Stefanie, Stojanovic, Kristina, Strobl, Daniel C., Babushku, Tea, Wang, Yan, Rambold, Ursula, Scheffler, Laura, Grath, Sonja, John-Robbert, Dorothy, Blum, Helmut, Feuchtinger, Annette, Blutke, Andreas, Weih, Falk, Kitamura, Daisuke, Rad, Roland, Strobl, Lothar J., Zimber-Strobl, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468873/
https://www.ncbi.nlm.nih.gov/pubmed/36110848
http://dx.doi.org/10.3389/fimmu.2022.913275