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CRX-527 induced differentiation of HSCs protecting the intestinal epithelium from radiation damage

Recently, Toll-like receptors (TLRs) have been extensively studied in radiation damage, but the inherent defects of high toxicity and low efficacy of most TLR ligands limit their further clinical transformation. CRX-527, as a TLR4 ligand, has rarely been reported to protect against radiation. We dem...

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Detalles Bibliográficos
Autores principales: Liu, Dongshu, Dong, Suhe, Liu, Cong, Du, Jicong, Wang, Sinian, Yu, Huijie, Li, Wei, Chen, Zhongmin, Peng, Renjun, Jiang, Qisheng, Zou, Mengying, Li, Fengsheng, Zhang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468934/
https://www.ncbi.nlm.nih.gov/pubmed/36110845
http://dx.doi.org/10.3389/fimmu.2022.927213