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Impaired Extraocular Muscle Innervation Is Present Before Eye Opening in a Mouse Model of Infantile Nystagmus Syndrome

PURPOSE: To determine if extraocular muscles (EOMs) from mice with nystagmus show abnormalities in myofiber composition and innervation, as seen in EOMs from human nystagmus patients, and to determine when in development those changes occur. METHODS: Balb/c albino mice were crossed to pigmented mice...

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Detalles Bibliográficos
Autores principales: Vemula, Sampath Kumar, Kim, Seoyoung A., Muvavarirwa, Tapiwa, Bell, Jessica L., Whitman, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469029/
https://www.ncbi.nlm.nih.gov/pubmed/36083589
http://dx.doi.org/10.1167/iovs.63.10.4