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Systemic interleukin-6 inhibition ameliorates acute neuropsychiatric phenotypes in a murine model of acute lung injury

Acute neuropsychiatric impairments occur in over 70% of patients with acute lung injury. Mechanical ventilation is a well-known precipitant of acute lung injury and is strongly associated with the development of acute delirium and anxiety phenotypes. In prior studies, we demonstrated that IL-6 media...

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Detalles Bibliográficos
Autores principales: Anwar, Faizan, Sparrow, Nicklaus A., Rashid, Mohammad Harun, Guidry, Gena, Gezalian, Michael M., Ley, Eric J., Koronyo-Hamaoui, Maya, Danovitch, Itai, Ely, E. Wesley, Karumanchi, S. Ananth, Lahiri, Shouri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469063/
https://www.ncbi.nlm.nih.gov/pubmed/36100846
http://dx.doi.org/10.1186/s13054-022-04159-x