Sialic Acid and Fucose Residues on the SARS-CoV-2 Receptor-Binding Domain Modulate IgG Antibody Reactivity

[Image: see text] The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is a conserved domain and a target for neutralizing antibodies. We defined the carbohydrate content of the recombinant RBD produced in different mammalian cells. We found a higher degree of complex-type N-linked glyc...

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Detalles Bibliográficos
Autores principales: Samuelsson, Ebba, Mirgorodskaya, Ekaterina, Nyström, Kristina, Bäckström, Malin, Liljeqvist, Jan-Åke, Nordén, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469093/
https://www.ncbi.nlm.nih.gov/pubmed/35980012
http://dx.doi.org/10.1021/acsinfecdis.2c00155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469093/
https://www.ncbi.nlm.nih.gov/pubmed/35980012
http://dx.doi.org/10.1021/acsinfecdis.2c00155

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