The Chinese herb Styrax triggers pharmacokinetic herb-drug interactions via inhibiting intestinal CYP3A

Human cytochrome P450 3A4 (hCYP3A4) is a predominant enzyme to trigger clinically relevant drug/herb-drug interactions (DDIs or HDIs). Although a number of herbal medicines have been found with strong anti-hCYP3A4 effects in vitro, the in vivo modulatory effects of herbal medicines on hCYP3A4 and th...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Zhang, Tiantian, Gong, Jiahao, Fang, Qinqin, Qi, Shenglan, Li, Mengting, Han, Yan, Liu, Wei, Ge, Guangbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469097/
https://www.ncbi.nlm.nih.gov/pubmed/36110541
http://dx.doi.org/10.3389/fphar.2022.974578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469097/
https://www.ncbi.nlm.nih.gov/pubmed/36110541
http://dx.doi.org/10.3389/fphar.2022.974578

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