Synergy by Perturbing the Gram-Negative Outer Membrane: Opening the Door for Gram-Positive Specific Antibiotics

[Image: see text] New approaches to target antibacterial agents toward Gram-negative bacteria are key, given the rise of antibiotic resistance. Since the discovery of polymyxin B nonapeptide as a potent Gram-negative outer membrane (OM)-permeabilizing synergist in the early 1980s, a vast amount of l...

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Detalles Bibliográficos
Autores principales: Wesseling, Charlotte M. J., Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469101/
https://www.ncbi.nlm.nih.gov/pubmed/35946799
http://dx.doi.org/10.1021/acsinfecdis.2c00193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469101/
https://www.ncbi.nlm.nih.gov/pubmed/35946799
http://dx.doi.org/10.1021/acsinfecdis.2c00193

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