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CRISPR/Cas9 ribonucleoprotein (RNP) complex enables higher viability of transfected cells in genome editing of acute myeloid cells

BACKGROUND: Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) has become an increasingly vital tool for modifying gene expression in a variety of cell types. Lentiviral transduction and electroporation are the two main approaches used to deliver CR...

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Detalles Bibliográficos
Autores principales: Cheng, Qinquan, Xia, Jing, Wang, Kaimin, Zhang, Yue, Chen, Yan, Zhong, Qi, Wang, Xue, Wu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469150/
https://www.ncbi.nlm.nih.gov/pubmed/36111017
http://dx.doi.org/10.21037/atm-22-3279