Itaconic acid facilitates inflammation abatement and alleviates liver ischemia-reperfusion injury by inhibiting NF-κB/NLRP3/caspase-1 inflammasome axis

BACKGROUND: Ischemia-reperfusion injury (IRI) severely limits the efficacy and donor source of liver transplantation, and the crucial step in alleviating it is to control inflammation. Itaconic acid is a metabolite produced by intrinsic immune cells (especially macrophages) in the inflammatory state...

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Detalles Bibliográficos
Autores principales: Ma, Ensi, Xing, Hao, Pei, Jiahao, Zhang, Quanbao, Li, Ruidong, Shen, Conghuan, Tao, Yifeng, Li, Jianhua, Ma, Zhenyu, Zhao, Jing, Wang, Zhengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469154/
https://www.ncbi.nlm.nih.gov/pubmed/36111043
http://dx.doi.org/10.21037/atm-22-3388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469154/
https://www.ncbi.nlm.nih.gov/pubmed/36111043
http://dx.doi.org/10.21037/atm-22-3388

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