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The role of pregnane X receptor (PXR) in substance metabolism

As a member of the nuclear receptor (NR) superfamily, pregnane X receptor (PXR; NR1I2) is a ligand-activated transcription factor that plays a crucial role in the metabolism of xenobiotics and endobiotics in mammals. The tissue distribution of PXR is parallel to its function with high expression in...

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Detalles Bibliográficos
Autores principales: Lv, Ye, Luo, Yi-Yang, Ren, Hui-Wen, Li, Cheng-Jie, Xiang, Zhi-Xin, Luan, Zhi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469194/
https://www.ncbi.nlm.nih.gov/pubmed/36111293
http://dx.doi.org/10.3389/fendo.2022.959902