An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer

BACKGROUND: Fatty acid synthase (FASN) expression is associated with a more aggressive breast cancer phenotype and is regulated downstream of receptor tyrosine kinase (RTK) signaling pathways. Recently, post transcriptional regulation of lipogenic transcripts have been demonstrated as being mediated...

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Detalles Bibliográficos
Autores principales: McClellan, Bryan, Gries, Paul, Harlow, Brittany, Tiziani, Stefano, Jolly, Christopher, deGraffenried, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469522/
https://www.ncbi.nlm.nih.gov/pubmed/36096767
http://dx.doi.org/10.1186/s12885-022-10062-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469522/
https://www.ncbi.nlm.nih.gov/pubmed/36096767
http://dx.doi.org/10.1186/s12885-022-10062-z

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