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Immunohistochemical staining of LEF-1 is a useful marker for distinguishing WNT-activated medulloblastomas
OBJECTIVES: To investigate lymphoid enhancer factor 1 (LEF-1) protein expression in medulloblastomas (MBs) and its correlation with molecular grouping of MBs. METHODS: Expressions of LEF-1 and β-catenin were detected by immunohistochemistry, and molecular grouping was performed based on the NanoStri...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469524/ https://www.ncbi.nlm.nih.gov/pubmed/36096860 http://dx.doi.org/10.1186/s13000-022-01250-3 |