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Immunohistochemical staining of LEF-1 is a useful marker for distinguishing WNT-activated medulloblastomas

OBJECTIVES: To investigate lymphoid enhancer factor 1 (LEF-1) protein expression in medulloblastomas (MBs) and its correlation with molecular grouping of MBs. METHODS: Expressions of LEF-1 and β-catenin were detected by immunohistochemistry, and molecular grouping was performed based on the NanoStri...

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Detalles Bibliográficos
Autores principales:	Wang, Depeng, Gong, Jie, Zhang, Hui, Liu, Yulu, Sun, Nannan, Hao, Xiaomeng, Mu, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469524/ https://www.ncbi.nlm.nih.gov/pubmed/36096860 http://dx.doi.org/10.1186/s13000-022-01250-3

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