Investigation of CRS-associated cytokines in CAR-T therapy with meta-GNN and pathway crosstalk

BACKGROUND: Chimeric antigen receptor T-cell (CAR-T) therapy is a new and efficient cellular immunotherapy. The therapy shows significant efficacy, but also has serious side effects, collectively known as cytokine release syndrome (CRS). At present, some CRS-related cytokines and their roles in CAR-...

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Detalles Bibliográficos
Autores principales: Wei, Zhenyu, Cheng, Qi, Xu, Nan, Zhao, Chengkui, Xu, Jiayu, Kang, Liqing, Lou, Xiaoyan, Yu, Lei, Feng, Weixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469618/
https://www.ncbi.nlm.nih.gov/pubmed/36100873
http://dx.doi.org/10.1186/s12859-022-04917-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469618/
https://www.ncbi.nlm.nih.gov/pubmed/36100873
http://dx.doi.org/10.1186/s12859-022-04917-2

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