CRISPR/Cas9 based blockade of IL-10 signaling impairs lipid and tissue homeostasis to accelerate atherosclerosis

Interleukin-10 (IL-10) is a widely recognized immunosuppressive factor. Although the concept that IL-10 executes an anti-inflammatory role is accepted, the relationship between IL-10 and atherosclerosis is still unclear, thus limiting the application of IL-10-based therapies for this disease. Emergi...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Haozhe, Guo, Jiabao, Yu, Qiongyang, Hou, Xinlin, Liu, Lili, Gao, Mingming, Wei, Lili, Zhang, Ling, Huang, Wei, Wang, Yuhui, Liu, George, Tontonoz, Peter, Xian, Xunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469689/
https://www.ncbi.nlm.nih.gov/pubmed/36110841
http://dx.doi.org/10.3389/fimmu.2022.999470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469689/
https://www.ncbi.nlm.nih.gov/pubmed/36110841
http://dx.doi.org/10.3389/fimmu.2022.999470

Ejemplares similares