Growth‐rate model predicts in vivo tumor response from in vitro data

A major challenge in oncology drug development is to elucidate why drugs that show promising results in cancer cell lines in vitro fail in mouse studies or human trials. One of the fundamental steps toward solving this problem is to better predict how in vitro potency translates into in vivo efficac...

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Detalles Bibliográficos
Autores principales: Diegmiller, Rocky, Salphati, Laurent, Alicke, Bruno, Wilson, Timothy R., Stout, Thomas J., Hafner, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469692/
https://www.ncbi.nlm.nih.gov/pubmed/35731938
http://dx.doi.org/10.1002/psp4.12836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469692/
https://www.ncbi.nlm.nih.gov/pubmed/35731938
http://dx.doi.org/10.1002/psp4.12836

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