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341 Repeats Is Not Enough for Methylation in a New Fragile X Mouse Model

Fragile X syndrome (FXS) is a leading monogenic cause of intellectual disability and autism spectrum disorders, spurring decades of intense research and a multitude of mouse models. So far, these models do not recapitulate the genetic underpinning of classical FXS—CGG repeat-induced methylation of t...

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Detalles Bibliográficos
Autores principales: Colvin, Steven, Lea, Nick, Zhang, Qiangge, Wienisch, Martin, Kaiser, Tobias, Aida, Tomomi, Feng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469916/
https://www.ncbi.nlm.nih.gov/pubmed/35977823
http://dx.doi.org/10.1523/ENEURO.0142-22.2022