Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling

The nutrient-activated mTORC1 (mechanistic target of rapamycin kinase complex 1) signaling pathway determines cell size by controlling mRNA translation, ribosome biogenesis, protein synthesis, and autophagy. Here, we show that vimentin, a cytoskeletal intermediate filament protein that we have known...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohanasundaram, Ponnuswamy, Coelho-Rato, Leila S., Modi, Mayank Kumar, Urbanska, Marta, Lautenschläger, Franziska, Cheng, Fang, Eriksson, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469959/
https://www.ncbi.nlm.nih.gov/pubmed/36099296
http://dx.doi.org/10.1371/journal.pbio.3001737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469959/
https://www.ncbi.nlm.nih.gov/pubmed/36099296
http://dx.doi.org/10.1371/journal.pbio.3001737

Ejemplares similares