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TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesicles

Host-pathogen dynamics are constantly at play during enteroviral infection. Coxsackievirus B (CVB) is a common juvenile enterovirus that infects multiple organs and drives inflammatory diseases including acute pancreatitis and myocarditis. Much like other enteroviruses, CVB is capable of manipulatin...

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Detalles Bibliográficos
Autores principales: Sawaged, Savannah, Mota, Thomas, Piplani, Honit, Thakur, Reetu, Lall, Deepti, McCabe, Elizabeth, Seo, Soojung, Sutterwala, Fayyaz S., Feuer, Ralph, Gottlieb, Roberta A., Sin, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469980/
https://www.ncbi.nlm.nih.gov/pubmed/36044516
http://dx.doi.org/10.1371/journal.ppat.1010350