L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling

BACKGROUND: Although codeine has been reported to enhance sexual activity by improving penile reflexes, it has been shown to impair fertility indices. Also, codeine impairs ovarian steroidogenesis and folliculogenesis. Nonetheless, whether or not codeine exerts an epigenetic effect remains unclear....

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Detalles Bibliográficos
Autores principales: Akhigbe, Roland Eghoghosoa, Afolabi, Oladele A., Ajayi, Ayodeji F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469994/
https://www.ncbi.nlm.nih.gov/pubmed/36099318
http://dx.doi.org/10.1371/journal.pone.0274411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469994/
https://www.ncbi.nlm.nih.gov/pubmed/36099318
http://dx.doi.org/10.1371/journal.pone.0274411

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