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L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling
BACKGROUND: Although codeine has been reported to enhance sexual activity by improving penile reflexes, it has been shown to impair fertility indices. Also, codeine impairs ovarian steroidogenesis and folliculogenesis. Nonetheless, whether or not codeine exerts an epigenetic effect remains unclear....
Autores principales: | Akhigbe, Roland Eghoghosoa, Afolabi, Oladele A., Ajayi, Ayodeji F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469994/ https://www.ncbi.nlm.nih.gov/pubmed/36099318 http://dx.doi.org/10.1371/journal.pone.0274411 |
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