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Identification of Functional HLA-A*01:01–Restricted Epstein-Barr Latent Membrane Protein 2–Specific T-Cell Receptors( )

BACKGROUND: Adoptive transfer of genetically engineered T cells expressing antigen-specific T-cell receptors (TCRs) is an appealing therapeutic approach for Epstein-Barr virus (EBV)–associated malignancies of latency type II/III that express EBV antigens (LMP1/2). Patients who are HLA-A*01:01 positi...

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Detalles Bibliográficos
Autores principales: Huisman, Wesley, Gille, Ilse, van der Maarel, Lieve E, Hageman, Lois, Morton, Laura T, de Jong, Rob C M, Heemskerk, Mirjam H M, Amsen, Derk, Falkenburg, J H Frederik, Jedema, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470112/
https://www.ncbi.nlm.nih.gov/pubmed/32808978
http://dx.doi.org/10.1093/infdis/jiaa512