Membrane-mediated dimerization potentiates PIP5K lipid kinase activity

The phosphatidylinositol 4-phosphate 5-kinase (PIP5K) family of lipid-modifying enzymes generate the majority of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] lipids found at the plasma membrane in eukaryotic cells. PI(4,5)P(2) lipids serve a critical role in regulating receptor activation, io...

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Detalles Bibliográficos
Autores principales: Hansen, Scott D, Lee, Albert A, Duewell, Benjamin R, Groves, Jay T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470164/
https://www.ncbi.nlm.nih.gov/pubmed/35976097
http://dx.doi.org/10.7554/eLife.73747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470164/
https://www.ncbi.nlm.nih.gov/pubmed/35976097
http://dx.doi.org/10.7554/eLife.73747

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