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Genetic control of RNA splicing and its distinct role in complex trait variation

Most genetic variants identified from genome-wide association studies (GWAS) in humans are noncoding, indicating their role in gene regulation. Previous studies have shown considerable links of GWAS signals to expression quantitative trait loci (eQTLs) but the links to other genetic regulatory mecha...

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Detalles Bibliográficos
Autores principales: Qi, Ting, Wu, Yang, Fang, Hailing, Zhang, Futao, Liu, Shouye, Zeng, Jian, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470536/
https://www.ncbi.nlm.nih.gov/pubmed/35982161
http://dx.doi.org/10.1038/s41588-022-01154-4