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Machine learning-based detection of immune-mediated diseases from genome-wide cell-free DNA sequencing datasets

The early detection of tissue and organ damage associated with autoimmune diseases (AID) has been identified as key to improve long-term survival, but non-invasive biomarkers are lacking. Elevated cell-free DNA (cfDNA) levels have been observed in AID and inflammatory bowel disease (IBD), prompting...

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Detalles Bibliográficos
Autores principales: Che, Huiwen, Jatsenko, Tatjana, Lannoo, Lore, Stanley, Kate, Dehaspe, Luc, Vancoillie, Leen, Brison, Nathalie, Parijs, Ilse, Van Den Bogaert, Kris, Devriendt, Koenraad, Severi, Sabien, De Langhe, Ellen, Vermeire, Severine, Verstockt, Bram, Van Calsteren, Kristel, Vermeesch, Joris Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470560/
https://www.ncbi.nlm.nih.gov/pubmed/36100603
http://dx.doi.org/10.1038/s41525-022-00325-w