Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Excessive inflammatory responses contribute to the pathogenesis and lethality of highly pathogenic human coronaviruses, but the underlying mechanism remains unclear. In this study, the N proteins of highly pathogenic human coronaviruses, including severe acute respiratory syndrome coronavirus (SARS-...

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Detalles Bibliográficos
Autores principales: Gao, Ting, Zhu, Lin, Liu, Hainan, Zhang, Xiaopeng, Wang, Tingting, Fu, Yangbo, Li, Hongzhen, Dong, Qincai, Hu, Yong, Zhang, Zhang, Jin, Jing, Liu, Zijing, Yang, Weihong, Liu, Yaoning, Jin, Yanwen, Li, Kaitong, Xiao, Yongjiu, Liu, Junli, Zhao, Huailong, Liu, Yue, Li, Ping, Song, Jibo, Zhang, Lu, Gao, Yuwei, Kang, Sisi, Chen, Shoudeng, Ma, Qingjun, Bian, Xiuwu, Chen, Wei, Liu, Xuan, Mao, Qing, Cao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470675/
https://www.ncbi.nlm.nih.gov/pubmed/36100602
http://dx.doi.org/10.1038/s41392-022-01133-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470675/
https://www.ncbi.nlm.nih.gov/pubmed/36100602
http://dx.doi.org/10.1038/s41392-022-01133-5

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