Cargando…
The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness
During COVID-19 pandemic, mutations of SARS-CoV-2 produce new strains that can be more infectious or evade vaccines. Viral RNA mutations can arise from misincorporation by RNA-polymerases and modification by host factors. Analysis of SARS-CoV-2 sequence from patients showed a strong bias toward C-to...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470679/ https://www.ncbi.nlm.nih.gov/pubmed/36100631 http://dx.doi.org/10.1038/s41598-022-19067-x |