The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

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During COVID-19 pandemic, mutations of SARS-CoV-2 produce new strains that can be more infectious or evade vaccines. Viral RNA mutations can arise from misincorporation by RNA-polymerases and modification by host factors. Analysis of SARS-CoV-2 sequence from patients showed a strong bias toward C-to...

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Detalles Bibliográficos
Autores principales: Kim, Kyumin, Calabrese, Peter, Wang, Shanshan, Qin, Chao, Rao, Youliang, Feng, Pinghui, Chen, Xiaojiang S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470679/
https://www.ncbi.nlm.nih.gov/pubmed/36100631
http://dx.doi.org/10.1038/s41598-022-19067-x

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