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Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome
Down syndrome (DS) induces a variable phenotype including intellectual disabilities and early development of Alzheimer’s disease (AD). Moreover, individuals with DS display accelerated aging that affects diverse organs, among them the brain. The Ts65Dn mouse is the most widely used model to study DS...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470680/ https://www.ncbi.nlm.nih.gov/pubmed/35767135 http://dx.doi.org/10.1007/s11064-022-03659-0 |