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Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome

Down syndrome (DS) induces a variable phenotype including intellectual disabilities and early development of Alzheimer’s disease (AD). Moreover, individuals with DS display accelerated aging that affects diverse organs, among them the brain. The Ts65Dn mouse is the most widely used model to study DS...

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Detalles Bibliográficos
Autores principales: Kirstein, Martina, Cambrils, Alba, Segarra, Ana, Melero, Ana, Varea, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470680/
https://www.ncbi.nlm.nih.gov/pubmed/35767135
http://dx.doi.org/10.1007/s11064-022-03659-0

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