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Transcription factor Sp1 regulates mitotic chromosome assembly and segregation

Aneuploidy is a pervasive feature of cancer cells that results from chromosome missegregation. Several transcription factors have been associated with aneuploidy; however, no studies to date have demonstrated that mammalian transcription factors directly regulate chromosome segregation during mitosi...

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Detalles Bibliográficos
Autores principales: Flashner, Samuel, Swift, Michelle, Sowash, Aislinn, Fahmy, Alexander N., Azizkhan-Clifford, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470683/
https://www.ncbi.nlm.nih.gov/pubmed/35916925
http://dx.doi.org/10.1007/s00412-022-00778-z