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GD2-specific chimeric antigen receptor-modified T cells for the treatment of refractory and/or recurrent neuroblastoma in pediatric patients

PURPOSE: This study aimed to evaluate the safety and efficacy of chimeric antigen receptor (CAR) disialoganglioside 2 (GD2)-specific (4SCAR-GD2) T cells for treatment of refractory and/or recurrent neuroblastoma (NB) in pediatric patients. EXPERIMENTAL DESIGN: A phase I clinical study using 4SCAR-GD...

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Detalles Bibliográficos
Autores principales: Yu, Lihua, Huang, Lulu, Lin, Danna, Lai, Xiaorong, Wu, Li, Liao, Xu, Liu, Jiale, Zeng, Yinghua, Liang, Lichan, Zhang, Guanmei, Wang, Bin, Wu, Zhu, Tao, Shaohua, Liu, Yuchen, Jiao, Cheng, Chang, Lung-Ji, Yang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470713/
https://www.ncbi.nlm.nih.gov/pubmed/34724115
http://dx.doi.org/10.1007/s00432-021-03839-5