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Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK

Tumor necrosis factor-alpha-induced protein 8-like 2 (TIPE2) possesses potent anti-inflammatory effect. However, if TIPE2 ameliorates sciatic nerve injury (SNI)-induced inflammation and pain remains undiscussed, and the underlying role TAK1 in it were unknown. To verify our imagine, we performed SNI...

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Detalles Bibliográficos
Autores principales: Sun, Xuehua, Li, Xinyou, Zhou, Youfei, Wang, Yufei, Liu, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470725/
https://www.ncbi.nlm.nih.gov/pubmed/35842555
http://dx.doi.org/10.1007/s11064-022-03671-4