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ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro

Background: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease characterized by the loss of motor neurons in cerebral cortex, brainstem and spinal cord. Numerous studies have demonstrated signs of oxidative stress in postmortem neuronal tissue, cerebrospinal fluid, plasma...

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Detalles Bibliográficos
Autores principales: Junghans, Maya, John, Felix, Cihankaya, Hilal, Schliebs, Daniel, Winklhofer, Konstanze F., Bader, Verian, Matschke, Johann, Theiss, Carsten, Matschke, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470831/
https://www.ncbi.nlm.nih.gov/pubmed/36119129
http://dx.doi.org/10.3389/fncel.2022.963169