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Identification of a novel histone phosphorylation prognostic signature in hepatocellular carcinoma based on bulk and single-cell RNA sequencing

BACKGROUND: Hepatocellular carcinoma (HCC) is the third leading cause of death in the world, characterized by high morbidity, poor prognosis and high mortality. Histone modifications regulate intracellular gene expression at the post-transcriptional level, and disturbances in the regulatory pattern...

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Detalles Bibliográficos
Autores principales: Fan, Lei, Xu, Ling, Tian, Shan, Zheng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470838/
https://www.ncbi.nlm.nih.gov/pubmed/36120466
http://dx.doi.org/10.3389/fendo.2022.965445