Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice

Glycosylphosphatidylinositol‐specific phospholipase D1 (GPLD1) hydrolyzes inositol phosphate linkages in proteins anchored to the cell membrane. Mice overexpressing GPLD1 show enhanced neurogenesis and cognition. Snell dwarf (DW) and growth hormone receptor knockout (GKO) mice show delays in age‐dep...

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Detalles Bibliográficos
Autores principales: Li, Xinna, Shi, Xiaofang, McPherson, Madaline, Hager, Mary, Garcia, Gonzalo G., Miller, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470888/
https://www.ncbi.nlm.nih.gov/pubmed/35930768
http://dx.doi.org/10.1111/acel.13685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470888/
https://www.ncbi.nlm.nih.gov/pubmed/35930768
http://dx.doi.org/10.1111/acel.13685

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