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Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice
Glycosylphosphatidylinositol‐specific phospholipase D1 (GPLD1) hydrolyzes inositol phosphate linkages in proteins anchored to the cell membrane. Mice overexpressing GPLD1 show enhanced neurogenesis and cognition. Snell dwarf (DW) and growth hormone receptor knockout (GKO) mice show delays in age‐dep...
Autores principales: | Li, Xinna, Shi, Xiaofang, McPherson, Madaline, Hager, Mary, Garcia, Gonzalo G., Miller, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470888/ https://www.ncbi.nlm.nih.gov/pubmed/35930768 http://dx.doi.org/10.1111/acel.13685 |
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