B cell‐intrinsic changes with age do not impact antibody‐secreting cell formation but delay B cell participation in the germinal centre reaction

Vaccines typically protect against (re)infections by generating pathogen‐neutralising antibodies. However, as we age, antibody‐secreting cell formation and vaccine‐induced antibody titres are reduced. Antibody‐secreting plasma cells differentiate from B cells either early post‐vaccination through th...

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Detalles Bibliográficos
Autores principales: Lee, Jia Le, Fra‐Bido, Sigrid C., Burton, Alice R., Innocentin, Silvia, Hill, Danika L., Linterman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470890/
https://www.ncbi.nlm.nih.gov/pubmed/35980826
http://dx.doi.org/10.1111/acel.13692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470890/
https://www.ncbi.nlm.nih.gov/pubmed/35980826
http://dx.doi.org/10.1111/acel.13692

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