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Adaptive cellular response of the substantia nigra dopaminergic neurons upon age‐dependent iron accumulation
Progressive iron accumulation in the substantia nigra in the aged human brain is a major risk factor for Parkinson's disease and other neurodegenerative diseases. Heavy metals, such as iron, produce reactive oxygen species and consequently oxidative stress in cells. It is unclear, however, how...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470899/ https://www.ncbi.nlm.nih.gov/pubmed/35984750 http://dx.doi.org/10.1111/acel.13694 |