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Adaptive cellular response of the substantia nigra dopaminergic neurons upon age‐dependent iron accumulation

Progressive iron accumulation in the substantia nigra in the aged human brain is a major risk factor for Parkinson's disease and other neurodegenerative diseases. Heavy metals, such as iron, produce reactive oxygen species and consequently oxidative stress in cells. It is unclear, however, how...

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Detalles Bibliográficos
Autores principales: Kwon, Kujin, Cho, Hwapyeong, Lee, Soyeon, Cho, Eun Jeong, Yu, Weonjin, Kok, Catherine Yen Li, Je, Hyunsoo Shawn, Kim, Jae‐Ick, Cho, Hyung Joon, Kwon, Taejoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470899/
https://www.ncbi.nlm.nih.gov/pubmed/35984750
http://dx.doi.org/10.1111/acel.13694