The Role of T Helper Type 2 (Th2) Cytokines in the Pathogenesis of Eosinophilic Granulomatosis with Polyangiitis (eGPA): an Illustrative Case and Discussion

PURPOSEOF REVIEW: The pathogenesis of eosinophilic granulomatosis with polyangiitis (eGPA) is driven largely by CD4 + type 2 helper T cells (Th2), B cells, and eosinophils. Interleukin (IL)-4 and IL-13 are critical cytokines in Th2 cell–mediated inflammation; however, inhibition of IL-4 and IL-13 do...

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Detalles Bibliográficos
Autores principales: Milne, Megan E., Kimball, Jack, Tarrant, Teresa K., Al-Rohil, Rami N., Leverenz, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Immunotherapy and Immunomodulators (B Vickery, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471022/
https://www.ncbi.nlm.nih.gov/pubmed/36103081
http://dx.doi.org/10.1007/s11882-022-01039-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471022/
https://www.ncbi.nlm.nih.gov/pubmed/36103081
http://dx.doi.org/10.1007/s11882-022-01039-w

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